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Nutraceuticals Research

Nutraceutical ingredients can be susceptible to oxidation, hydrolysis, light degradation, moisture and temperature-related changes.

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Stability studies may evaluate:

  • Appearance, physical properties and moisture
  • Assay, marker/bioactive content and degradation products
  • pH and dissolution
  • Microbial quality
  • Packaging compatibility

Testing depends on the product, formulation and intended storage conditions.

Analytical Characterization

Analytical evaluation may include:

  • Active ingredients and bioactive constituents
  • Marker compounds, vitamins and phytochemicals
  • Degradation products and contaminants

Techniques: HPLC | HPTLC | GC/GC-MS | UV-Visible Spectroscopy | Other Suitable Methods

Nutraceutical Product Development Workflow

Ingredient Characterization → Standardization & Analytical Evaluation → Preformulation → Compatibility Studies → Dosage-Form Selection → Formulation Development → QbD/DoE Optimization → Product Characterization → Stability Evaluation → Packaging Considerations → Scale-Up.

Challenges We Address

  • Poor Solubility and Low Dissolution
  • Poor Stability and Bioactive Degradation
  • Unpleasant Taste/Odor
  • Ingredient Incompatibility
  • Batch-to-Batch Variability
  • Poor Bioavailability
  • Moisture Sensitivity and Oxidative Instability
  • Difficult Standardization and Dosage-Form Challenges

Nutraceuticals & Advanced Delivery

Advanced delivery technologies may help address specific formulation challenges:

  • Poorly Soluble Bioactives: Nanoemulsions, nanoparticles or phytosomes
  • Unstable Bioactives: Encapsulation or liposomal delivery
  • Short Residence Time: Mucoadhesive or controlled-release systems
  • Unpleasant Taste: Encapsulation or taste-masking technologies

Why Partner with HSP Research Group for Nutraceutical Research?

  • Ingredient-to-Product Approach: From ingredient characterization to formulation optimization.
  • Analytical & Formulation Integration: Linking chemical analysis with product performance.
  • Advanced Delivery Technologies: Exploring nano-, lipid-, vesicular and controlled-delivery systems.
  • Standardization Focus: Consistent marker content and reproducible quality.
  • QbD/DoE-Based Development: Systematic formulation and process optimization.
  • Product Development Perspective: Considering stability, manufacturability, packaging and scalability.

From Bioactive Ingredient to Finished Nutraceutical Product

HSP Research Group LLP aims to support the development of scientifically characterized, optimized and stable nutraceutical products.

Functional Ingredients | Botanical Extracts | Phytochemicals | Vitamins | Minerals | Bioactive Compounds | Nutraceutical Formulations | Advanced Delivery Systems

Have a Nutraceutical Development Challenge?

Partner with HSP Research Group LLP to discuss ingredient characterization, formulation development, standardization, advanced delivery and product optimization.