Nutraceutical ingredients can be susceptible to oxidation, hydrolysis, light degradation, moisture and temperature-related changes.
Nutraceuticals Research
Stability studies may evaluate:
- Appearance, physical properties and moisture
- Assay, marker/bioactive content and degradation products
- pH and dissolution
- Microbial quality
- Packaging compatibility
Testing depends on the product, formulation and intended storage conditions.
Analytical Characterization
Analytical evaluation may include:
- Active ingredients and bioactive constituents
- Marker compounds, vitamins and phytochemicals
- Degradation products and contaminants
Techniques: HPLC | HPTLC | GC/GC-MS | UV-Visible Spectroscopy | Other Suitable Methods
Nutraceutical Product Development Workflow
Ingredient Characterization → Standardization & Analytical Evaluation → Preformulation → Compatibility Studies → Dosage-Form Selection → Formulation Development → QbD/DoE Optimization → Product Characterization → Stability Evaluation → Packaging Considerations → Scale-Up.
Challenges We Address
- Poor Solubility and Low Dissolution
- Poor Stability and Bioactive Degradation
- Unpleasant Taste/Odor
- Ingredient Incompatibility
- Batch-to-Batch Variability
- Poor Bioavailability
- Moisture Sensitivity and Oxidative Instability
- Difficult Standardization and Dosage-Form Challenges
Nutraceuticals & Advanced Delivery
Advanced delivery technologies may help address specific formulation challenges:
- Poorly Soluble Bioactives: Nanoemulsions, nanoparticles or phytosomes
- Unstable Bioactives: Encapsulation or liposomal delivery
- Short Residence Time: Mucoadhesive or controlled-release systems
- Unpleasant Taste: Encapsulation or taste-masking technologies
Why Partner with HSP Research Group for Nutraceutical Research?
- Ingredient-to-Product Approach: From ingredient characterization to formulation optimization.
- Analytical & Formulation Integration: Linking chemical analysis with product performance.
- Advanced Delivery Technologies: Exploring nano-, lipid-, vesicular and controlled-delivery systems.
- Standardization Focus: Consistent marker content and reproducible quality.
- QbD/DoE-Based Development: Systematic formulation and process optimization.
- Product Development Perspective: Considering stability, manufacturability, packaging and scalability.
From Bioactive Ingredient to Finished Nutraceutical Product
HSP Research Group LLP aims to support the development of scientifically characterized, optimized and stable nutraceutical products.
Functional Ingredients | Botanical Extracts | Phytochemicals | Vitamins | Minerals | Bioactive Compounds | Nutraceutical Formulations | Advanced Delivery Systems
Have a Nutraceutical Development Challenge?
Partner with HSP Research Group LLP to discuss ingredient characterization, formulation development, standardization, advanced delivery and product optimization.
